Concepedia

Design, synthesis, and antimalarial activity of structural chimeras of thiosemicarbazone and ferroquine analogues

Christophe Biot, Bruno Pradines, Marie-Hélène Sergeant, Jiří Gut, Philip J. Rosenthal, Kelly Chibale

Bioorganic & Medicinal Chemistry Letters · 2007 · 82 citations · 25 references

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References

25

2-Acetylpyridine thiosemicarbazones. 1. A new class of potential antimalarial agents

Daniel L. Klayman, J. F. BARTOSEVICH, T. Scott Griffin et al. · Journal of Medicinal Chemistry · 1979 · 428 citations

, , +15

A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum.

Philip J. Rosenthal, James H. McKerrow, M Aikawa et al. · Journal of Clinical Investigation · 1988 · 328 citations · Full text

, , +17

Synthesis and Structure−Activity Relationships of Parasiticidal Thiosemicarbazone Cysteine Protease Inhibitors against <i>Plasmodium falciparum</i>, <i>Trypanosoma brucei</i>, and <i>Trypanosoma cruzi</i>

Doron C. Greenbaum, Zachary B. Mackey, Elizabeth Hansell et al. · Journal of Medicinal Chemistry · 2004 · 254 citations · Full text

, , +17

Design, synthesis and anti-plasmodial evaluation in vitro of new 4-aminoquinoline isatin derivatives

Idan Chiyanzu, Cailean Clarkson, Peter J. Smith et al. · Bioorganic & Medicinal Chemistry · 2005 · 175 citations

, , +8

A novel artemisinin–quinine hybrid with potent antimalarial activity

John Walsh, David Coughlan, Nicola R Heneghan et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 168 citations

, , +14