Structure determination of LL-F28249α, β, γ, and λ, potent antiparasitic macrolides from Streptomyces cyaneogriseus ssp. noncyanogenus

Abstract

The structures of four antiparasitic macrocyclic lactones, LL-F28249α, λ, β, and γ(1)–(4) derived from the actinomycete Streptomyces cyaneogriseus ssp. noncyanogenus, were determined by spectroscopic methods and by X-ray crystallography of the γ-component (4).