Electrochemical detection of thrombin by sandwich approach using antibody and aptamer

Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase

Craig Tuerk, Larry Gold · Science · 1990 · 10.4K citations

Life Sciences, Microbiology, Molecular Biology +15

In vitro selection of RNA molecules that bind specific ligands

Andrew D. Ellington, Jack W. Szostak · Nature · 1990 · 9.7K citations

Life Sciences, Molecular Biology, Rna Processing +13

Selection of single-stranded DNA molecules that bind and inhibit human thrombin

Louis C. Bock, Linda C. Griffin, John Latham et al. · Nature · 1992 · 2.5K citations

Medicine, Biotechnology, Molecular Biology +13

Label‐Free Electronic Detection of Thrombin in Blood Serum by Using an Aptamer‐Based Sensor

Yi Xiao, Arica A. Lubin, Alan J. Heeger et al. · Angewandte Chemie International Edition · 2005 · 805 citations

Engineering, Biochemistry, Chemistry +16

Aptamer-Functionalized Au Nanoparticles for the Amplified Optical Detection of Thrombin

Valeri Pavlov, Yi Xiao, Bella Shlyahovsky et al. · Journal of the American Chemical Society · 2004 · 691 citations

Engineering, Biomedical Engineering, Materials Science +17