Organic & Biomolecular Chemistry · 2011 · 246 citations · 78 references
PharmacyMedicinal ChemistryPharmacologyDrug DesignDrug DiscoveryMolecular RecognitionAnion RecognitionDrug-receptor InteractionsLigand BindingLigand-based DesignReceptor-ligand InteractionsStructural Basis Of RecognitionAnion Receptor DesignImidazole ChemistryImidazolylidene Ligands
Due to its amphoteric nature the imidazole ring can function as selective and effective anion and/or cation and even neutral organic molecules receptor system. As a result, the design of new multichannel imidazole-based receptors capable of recognizing different types of analytes is strongly demanded. This review summarizes the most recent and relevant advances in this area.
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