<i>Epidermal growth factor receptor</i>gene amplification and expression in disseminated pediatric low-grade gliomas

Abstract

The high rate of EGFR gene amplification and protein expression in disseminated pediatric LGGs is intriguing and may have implications for our understanding of the role of EGFR in glioma genesis. Targeted therapies may be available for these children. Larger-scale studies are needed to establish further these findings.