Increased prevalence of insulin resistance in women with a history of recurrent pregnancy loss

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

David R. Matthews, J P Hosker, A. Rudenski et al. · Diabetologia · 1985 · 31.4K citations · Full text

Medicine, Endocrinology, Physiology +17

Glucose clamp technique: a method for quantifying insulin secretion and resistance.

R. A. DeFronzo, J. D. Tobin, R Andres · American Journal of Physiology-Endocrinology and Metabolism · 1979 · 7.5K citations

Medicine, Biochemistry, Endocrinology +17

Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity.

Enzo Bonora, Giovanni Targher, Maria Alberiche et al. · Diabetes Care · 2000 · 2.5K citations · Full text

Medicine, Endocrinology, Comparative Endocrinology +7

Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy

Elsy Velázquez, Soaira Mendoza, T Hamer et al. · Metabolism · 1994 · 874 citations

Medicine, Endocrinology, Gynecology +17

Effects of Metformin on Spontaneous and Clomiphene-Induced Ovulation in the Polycystic Ovary Syndrome

John E. Nestler, Daniela Jakubowicz, William S. Evans et al. · New England Journal of Medicine · 1998 · 789 citations · Full text

Medicine, Endocrinology, Pharmacology +9