Reduction of Some Functional Groups with Zirconium Tetrachloride/Sodium Borohydride

Shinichi Itsuno, Yoshiki Sakurai, Koichi Ito

Synthesis · 1988 · 73 citations · 0 references

Concepts

Abstract

Novel reducing agent prepared from zirconium tetrachloride and sodium borohydride reduces various functional groups including C=O double bonds, C=N double bonds and C≡N triple bonds in excellent yield (85-96%) under mild condition.