Immunocytochemistry with Cytokeratin 19 and Anti-Human Mesothelial Cell Antibody (HBME1) Increases the Diagnostic Accuracy of Thyroid Fine-Needle Aspirations: Preliminary Report of 150 Liquid-Based Fine-Needle Aspirations with Histological Control

Abstract

ICC of thyroid FNAs with cytokeratin 19 and HBME1 antibodies can reduce the false-positive and false-negative results of single morphological analyses. It can increase the sensitivity and specificity of diagnosis, thus improving diagnostic accuracy and reducing the need for surgical controls.