Effect of Tri-Iodothyronine on Rate of Alcohol Oxidation in Dogs

Abstract

IT has been reported1 that tri-iodothyronine will accelerate the metabolism of ethyl alcohol. If this is true such an effect would have considerable implications for clinical practice as a relatively simple technic that could quickly restore a hostile or comatose inebriate to relative sobriety. It was therefore thought important to attempt to confirm these observations.Method and MaterialsFive mongrel dogs (4 male and 1 female) weighing from 20 to 25 kg. each were used in the experiment. After a sixteen-hour fast the animals were given 2 gm. of ethyl alcohol per kilogram of body weight as a 15 . . .