Publication | Closed Access
Rapid and Marked Inhibition of Rat-Liver RNA Polymerase by Aflatoxin B <sub>1</sub>
89
Citations
7
References
1966
Year
PathologyMolecular BiologyDrug ResistanceHepatotoxicityAntisense TherapyMarked InhibitionRat-liver Rna PolymeraseBiochemistryLiver PhysiologyDna-directed Rna SynthesisGene Expression35-To 70-Percent InhibitionPharmacologyDrug-induced Liver InjuryHepatologyNatural SciencesAflatoxin BLiver DiseaseMicrobiologyMedicineGenome Editing
From 15 minutes to 2 hours after the administration of aflatoxin B(1) invivo there is a 35-to 70-percent inhibition of DNA-directed RNA synthesis. The inhibition was reversed 12 and 24 hours later.
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