Comparison of visual performance with an aspheric intraocular lens and a spherical intraocular lens

Abstract

PURPOSE: To compare the visual performance after implantation of the Akreos Adapt Advanced Optics aspheric intraocular lens (IOL) and the Sensar AR40e spherical acrylic IOL. SETTING: Eye Department, Southampton University Hospital, United Kingdom. DESIGN: Randomized masked single-center clinical trial. METHODS: Patients with bilateral cataract who were older than 50 years with a biometry-predicted IOL power between 10.0 diopters (D) and 30.0 D were recruited. Outcome measures included corrected distance visual acuity (CDVA) using a high-contrast logMAR chart, contrast sensitivity measured with the Pelli-Robson chart, range of accommodation using the Royal Air Force (RAF) rule, pseudoaccommodation and mesopic and scotopic pupil diameters measured with a power refractor, and patient satisfaction evaluated using a previously validated questionnaire 3 months after second-eye surgery. RESULTS: The difference in the mean value between the 2 IOLs (40 patients) was 0.015 (95% confidence interval [CI], 0.0009 to 0.070) for CDVA in favor of the spherical IOL, 0.02 (95% CI, -0.0534 to 0.0159) for contrast sensitivity, and 0.05 (95% CI, -1.90 to +2.90) for range of accommodation. Questionnaire results showed no difference in dysphotopsia or patient satisfaction between the 2 IOLs. CONCLUSIONS: Although there were no statistically significant differences in contrast sensitivity, range of accommodation, dysphotopsia, or subjective patient satisfaction or preference between the 2 IOLs, the difference in CDVA was statistically significant, but not clinically important (relative difference 1.5%), in favor of the spherical IOL. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.