Nef Harbors a Major Determinant of Pathogenicity for an AIDS-like Disease Induced by HIV-1 in Transgenic Mice

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

Harry W. Kestier, D J Ringler, Kazuyasu Mori et al. · Cell · 1991 · 1.6K citations

Life Sciences, Genetics, Molecular Biology +12

LAT

Joanne Sloan‐Lancaster, J. Kitchen, Ronald P. Trible et al. · Cell · 1998 · 1.3K citations · Full text

Genomic Structure of an Attenuated Quasi Species of HIV-1 from a Blood Transfusion Donor and Recipients

Nicholas J. Deacon, Anna Tsykin, A. Solomon et al. · Science · 1995 · 1.2K citations

Life Sciences, Molecular Biology, Molecular Genetics +14

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes

Kathleen L. Collins, Benjamin K. Chen, Spyros A. Kalams et al. · Nature · 1998 · 1K citations

Life Sciences, Immunology, Infectious Diseases +15

Absence of Intact nef Sequences in a Long-Term Survivor with Nonprogressive HIV-1 Infection

Frank Kirchhoff, Thomas C. Greenough, Doreen B. Brettler et al. · New England Journal of Medicine · 1995 · 1K citations · Full text

Life Sciences, Immunology, Infectious Diseases +10