Synlett · 2015 · 62 citations · 0 references
Natural SciencesChemistryCatalysisOrganic ChemistryCatalyst DesignCatalyst SynthesisCatalytic MaterialsHeterogeneous CatalysisMetal CatalysisOrganic SynthesisAlkylation ReactionsAlkyne ActivationCopper CatalysisCopper-catalyzed CouplingTransition Metal-catalyzed Synthesis
Copper-catalyzed semihydrogenation of internal alkynes has been developed. The reaction proceeds under an atmosphere of hydrogen (5 atm) at 100 °C in the presence of a readily available [(PPh<sub>3</sub>)CuCl]<sub>4</sub> catalyst to give various <i>Z</i>-alkenes stereoselectively.