Concepedia

Unnatural enantiomer of chaetocin shows strong apoptosis-inducing activity through caspase-8/caspase-3 activation

Yuou Teng, Katsuya Iuchi, Eriko Iwasa, Shinya Fujishiro, Yoshitaka Hamashima, Kosuke Dodo, Mikiko Sodeoka

Bioorganic & Medicinal Chemistry Letters · 2010 · 32 citations · 13 references

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References

13

Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9

Dorothea Greiner, Tiziana Bonaldi, Ragnhild Eskeland et al. · Nature Chemical Biology · 2005 · 520 citations · Full text

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Total Synthesis of (+)-Chaetocin and its Analogues: Their Histone Methyltransferase G9a Inhibitory Activity

Eriko Iwasa, Yoshitaka Hamashima, Shinya Fujishiro et al. · Journal of the American Chemical Society · 2010 · 231 citations

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Chaetocin: a promising new antimyeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress

Crescent R. Isham, Jennifer D. Tibodeau, Wendy Jin et al. · Blood · 2006 · 199 citations · Full text

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Isolierung und Strukturaufklärung von Chaetocin

Daniel Hauser, Hans Peter Weber, H. P. Siǵǵ · Helvetica Chimica Acta · 1970 · 156 citations

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The Anticancer Agent Chaetocin Is a Competitive Substrate and Inhibitor of Thioredoxin Reductase

Jennifer D. Tibodeau, Linda M. Benson, Crescent R. Isham et al. · Antioxidants and Redox Signaling · 2008 · 101 citations · Full text

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