DNA methylation of circulating DNA: a marker for monitoring efficacy of neoadjuvant chemotherapy in breast cancer patients

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.

Marianne Frommer, Louise E. McDonald, David Millar et al. · Proceedings of the National Academy of Sciences · 1992 · 3.3K citations

Life Sciences, Genetics, Molecular Biology +14

Preoperative Chemotherapy in Patients With Operable Breast Cancer: Nine-Year Results From National Surgical Adjuvant Breast and Bowel Project B-18

Norman Wolmark, J. Wang, E. Mamounas et al. · JNCI Monographs · 2001 · 1.3K citations · Full text

Medicine, Oncology, Surgery +17

Promoter Hypermethylation and BRCA1 Inactivation in Sporadic Breast and Ovarian Tumors

Manel Esteller · JNCI Journal of the National Cancer Institute · 2000 · 1.2K citations · Full text

Medicine, Genetics, Oncology +16

Randomized trial of chemoendocrine therapy started before or after surgery for treatment of primary breast cancer.

T.J. Powles, Tamas Hickish, Andreas Makris et al. · Journal of Clinical Oncology · 1995 · 352 citations

Medicine, Oncology, Surgery +17