Myocardial Gene Expression in Dilated Cardiomyopathy Treated with Beta-Blocking Agents

Time course of improvement in left ventricular function, mass and geometry in patients with congestive heart failure treated with beta-adrenergic blockade

Shelley Hall, Carlos G. Cigarroa, Lucille Marcoux et al. · Journal of the American College of Cardiology · 1995 · 532 citations

Heart Failure, Device Therapy, Cardiovascular Disease +9

Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hypertrophied, failing ventricular myocardium.

Brian D. Lowes, Wayne Minobe, William T. Abraham et al. · Journal of Clinical Investigation · 1997 · 501 citations · Full text

Cardiac Muscle, Heart Failure, Genetics +19

Comparative Hemodynamic, Left Ventricular Functional, and Antiadrenergic Effects of Chronic Treatment With Metoprolol Versus Carvedilol in the Failing Heart

Edward M. Gilbert, William T. Abraham, Stephanie L. Olsen et al. · Circulation · 1996 · 443 citations

Ejection fraction, peak exercise oxygen consumption, cardiothoracic ratio, ventricular arrhythmias, and plasma norepinephrine as determinants of prognosis in heart failure

Jay N. Cohn, Gary R. Johnson, Ralph Shabetai et al. · 1993 · 432 citations

Ventricular Arrhythmias, Heart Failure, Complex Pathophysiology +12

Left Ventricular Remodeling With Carvedilol in Patients With Congestive Heart Failure Due to Ischemic Heart Disease fn1fn1This study was funded by a grant from SmithKline Beecham; however, the study was initiated, conducted, analyzed and reported by the Australia–New Zealand Heart Failure Research Collaborative Group independently of the sponsor. The Clinical Trials Research Unit is supported by a programme grant from the Health Research Council of New Zealand.

Robert N. Doughty, Gillian Whalley, Greg Gamble et al. · Journal of the American College of Cardiology · 1997 · 419 citations

Cardiomyopathy, Heart Failure, Smithkline Beecham +10