Archives of Disease in Childhood · 2003 · 77 citations · 10 references
HypertensionAntifibrotic TherapyPulmonary Arterial HypertensionPulmonary CirculationCardiovascular DiseasePharmacologyPulmonary PharmacologyPulmonary HypertensionPharmacotherapyPulmonary MedicinePoor PrognosisChronic Pulmonary HypertensionPublic HealthMedicineCardiologyPulmonary Vascular Disease
Severe, chronic pulmonary hypertension in childhood is uncommon, difficult to treat, and carries a poor prognosis. Sildenafil (Viagra, Pfizer) has been used successfully in adults with pulmonary hypertension as monotherapy or in combination with inhaled prostacyclin. Here we report on its use in three children.
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Bosentan Therapy for Pulmonary Arterial Hypertension
Lewis J. Rubin, David B. Badesch, Robyn J. Barst et al. · New England Journal of Medicine · 2002 · 2.7K citations · Full text
Sildenafil Inhibits Hypoxia-Induced Pulmonary Hypertension
Lan Zhao, Nicola A. Mason, Nicholas W. Morrell et al. · Circulation · 2001 · 484 citations · Full text
Vasodilator Therapy for Primary Pulmonary Hypertension in Children
Robyn J. Barst, Greg Maislin, Alfred P. Fishman · Circulation · 1999 · 425 citations