Concepedia

The influence of class II transactivator and interleukin‐6 polymorphisms on the production of antibodies to donor human leucocyte antigen mismatches in renal allograft recipients

Jane Worthington, Shealynn B. Harris, Spencer D. Martin

International Journal of Immunogenetics · 2009 · 13 citations · 10 references

DOI

Concepts

Abstract

The influence of polymorphisms in the CIITA and IL-6 genes on donor-specific human leucocyte antigen antibody production was investigated in a cohort of renal transplant recipients and their donors. CIITA and IL-6 single nucleotide polymorphisms were found to be associated with donor-specific human leucocyte antigen antibody production post-transplantation.

References

10

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, , +24

Regulation of MHC Class II Expression by Interferon-γ Mediated by the Transactivator Gene CIITA

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Catherine Terry, Valérie Loukaci, Fiona R. Green · Journal of Biological Chemistry · 2000 · 796 citations · Full text

MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction

Maria Swanberg, Olle Lidman, Leonid Padyukov et al. · Nature Genetics · 2005 · 345 citations

, , +11

Posttransplantation production of donor HLA-specific antibodies as a predictor of renal transplant outcome1

Judith Worthington, Susan Martin, Dalia M. Al-Husseini et al. · Transplantation · 2003 · 299 citations