Synthesis of an RGD‐Sialyl‐Lewis^X Glycoconjugate: A New Highly Active Ligand for P‐Selectin^**

Abstract

Complex saccharide-peptide conjugates are accessible through an efficient fragment condensation in which the partially protected RGD peptide is coupled with the sialyl LewisX amine unit to form 1. Compound 1 is the most potent antagonist for P-select-in yet reported.