Suzuki–Miyaura Cross‐Coupling under Solvent‐Free Conditions

Abstract

Abstract A solvent‐free reaction protocol for Suzuki–Miyaura cross‐couplings was developed. (Hetero)aryl bromides and chlorides are coupled with pinacol arylboronates in high yields. The reaction is catalyzed by conventional bis(triphenylphosphine)palladium(II) chloride [(PPh 3 ) 2 PdCl 2 ] and/or palladium(II) acetate/SPhos [Pd(OAc) 2 /SPhos] under air. magnified image