Nitric oxide activates Ca2+-activated K+ channels in cultured bovine adrenal chromaffin cells

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Owen P. Hamill, Alain Marty, Erwin Neher et al. · Pflügers Archiv - European Journal of Physiology · 1981 · 18.5K citations

Natural Sciences, Biophysics, Cell Biology +16

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

Hiroyoshi Hidaka, Masaki Inagaki, Sachiyo Kawamoto et al. · Biochemistry · 1984 · 2.7K citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle

Victoria M. Bolotina, Soheil Najibi, James Palacino et al. · Nature · 1994 · 1.7K citations

Natural Sciences, Biophysics, Physiology +12

Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta.

William Martin, G. Villani, D Jothianandan et al. · Journal of Pharmacology and Experimental Therapeutics · 1985 · 1.3K citations

Medicine, Pharmacology, Physiology +8

Regulation of Arterial Tone by Activation of Calcium-Dependent Potassium Channels

Joseph E. Brayden, Mark T. Nelson · Science · 1992 · 933 citations

Life Sciences, Pharmacology, Physiology +17