Nicorandil may be associated with gastrointestinal ulceration

Abstract

Nicorandil (Ikorel; Rhone-Poulenc Rorer, Guildford) is associated with mouth and anal ulcers,1–4 but we are not aware of any previous reports of association with gastrointestinal ulceration. A 69 year old woman had had percutaneous coronary intervention and a stent inserted into her left anterior descending artery two years before presentation. She had recurrent angina, and her general practitioner increased her dose of nicorandil to 30 mg twice a …