Factors influencing variability of localisation of antibodies to carcinoembryonic antigen (CEA) in patients with colorectal carcinoma – implications for radioimmunotherapy

Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure.

R K Jain, Laurence T. Baxter · PubMed · 1988 · 715 citations

Medicine, Cancer Biology, Oncology +17

Immunohistological distribution of 5T4 antigen in normal and malignant tissues

PJ Southall, GM Boxer, K. D. Bagshawe et al. · British Journal of Cancer · 1990 · 185 citations · Full text

Medicine, Oncology, Pathology +13

Penetration and binding of radiolabeled anti-carcinoembryonic antigen monoclonal antibodies and their antigen binding fragments in human colon multicellular tumor spheroids.

R. M. Sutherland, F. Buchegger, Magali Schreyer et al. · PubMed · 1987 · 151 citations

Medicine, Cancer Biology, Oncology +17

Nonuniformity of tumor dose in radioimmunotherapy.

John L. Humm, Loren Cobb · PubMed · 1990 · 122 citations

Medicine, Nuclear Medicine, Oncology +16

Radioimmunoguided surgery using monoclonal antibody

Edward W. Martin, Cathy M. Mojzisik, George H. Hinkle et al. · The American Journal of Surgery · 1988 · 106 citations

Life Sciences, Immunology, Surgery +10