Concepedia

A benzophenazine derivative,N-β-dimethylaminoethyl 9-carboxy-5-hydroxy-10-methoxy-benzo[a]phenazine-6-carboxamide, as a new antitumor agent against multidrug-resistant and sensitive tumors

Takashi Tsuruo, Mikihiko Naito, R Takamori, Satomi Tsukahara, Junko Yamabe-Mitsuhashi, Akiko Yamazaki, Tomoko Oh‐hara, Yojiro Sudo, Shiro Nakaike, Takehiro Yamagishi

Cancer Chemotherapy and Pharmacology · 1990 · 12 citations · 18 references

DOI

Concepts

References

18

Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase II

K M Tewey, Thomas C. Rowe, Liu Yang et al. · Science · 1984 · 1.5K citations

, , +17

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.

Takashi Tsuruo, Harumi Iida, Shigeru Tsukagoshi et al. · PubMed · 1981 · 1.5K citations

, , +7

Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.

Takashi Tsuruo, Harumi Iida, Shigeru Tsukagoshi et al. · PubMed · 1982 · 664 citations

, , +17

Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide.

Eric M. Nelson, K M Tewey, Leroy F. Liu · Proceedings of the National Academy of Sciences · 1984 · 562 citations

, , +15

Altered surface membrane glycoproteins in Vinca alkaloid-resistant human leukemic lymphoblasts.

William T. Beck, Thomas J. J. Mueller, Lee R. Tanzer · PubMed · 1979 · 477 citations

, , +11