Effect of Moderate Hypothermia on Experimental Severe Subarachnoid Hemorrhage, as Evaluated by Apparent Diffusion Coefficient Changes

Abstract

This model of severe SAH in rats causes significant ADC changes, which are reversible by application of moderate hypothermia even when it is induced after a 60-minute delay. These findings support the concept of moderate hypothermia exerting a neuroprotective effect in severe SAH.