A geranylgeranyltransferase for rhoA p21 distinct from the farnesyltransferase for ras p21A

All ras proteins are polyisoprenylated but only some are palmitoylated

John F. Hancock, Anthony I. Magee, Julie E. Childs et al. · Cell · 1989 · 1.8K citations

Protein Chemistry, Protein Function, Biochemistry +6

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

John F. Hancock, Hugh Paterson, Christopher J. Marshall · Cell · 1990 · 1.1K citations

Proteinlipid Interaction, Biochemistry, Plasma Membrane +13

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

Yuval Reiss, Joseph L. Goldstein, Miguel C. Seabra et al. · Cell · 1990 · 814 citations

Biochemistry, Purified P21ras Farnesyl, Protein Transport +2

The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells.

Pierre Teilhard de Chardin, Patrice Boquet, Pascal Madaule et al. · The EMBO Journal · 1989 · 527 citations · Full text

Protein Function, Molecular Physiology, Biochemistry +12

A novel ras-related gene family

Pascal Madaule, Richard Axel · Cell · 1985 · 491 citations

Genetics, Genomic Mechanism, Molecular Genetics +4