OXA-48-Producing Enterobacteriaceae Causing Bacteremia, United Arab Emirates

Abstract

Carbapenems offer an important treatment option for infections caused by Enterobacteriaceae, in particular those producing extended-spectrum b-lactamase (ESBL). However, several classes of carbapenemases have emerged with the increased use of carbapenems. ] E. coli and K. pneumoniae clinical isolates identified from blood cultures were collected between 2011 and 2012. Only one isolate was collected per patient. A total of 80 ESBL-producing and 150 non-ESBL-producing isolates were collected, as determined by Vitek2 (bioMe rieux, Marcy l'Etoile, France). The isolates were then screened for carbapenem non-susceptibility by growth on Luria-Bertani agar plates containing 0.5 mg/ml of ertapenem. As a result,