Sepsis-associated Cholestasis in Adult Patients: A Prospective Study

APACHE II

William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine · 1985 · 13.7K citations

Medicine, Internal Medicine, Clinical Classification Systems +16

APACHE II-A Severity of Disease Classification System

William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine · 1986 · 13.4K citations

Health Professions, Biostatistics, Clinical Classification Systems +12

The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure

Jean‐Louis Vincent, Rui P. Moreno, Jukka Takala et al. · Intensive Care Medicine · 1996 · 11.6K citations

Veterinary Medicine, Internal Medicine, Critical Care Medicine +12

Diagnostic and Prognostic Implications of Endotoxemia in Critical Illness: Results of the MEDIC Study

John C. Marshall, Debra Foster, Jean‐Louis Vincent et al. · The Journal of Infectious Diseases · 2004 · 360 citations · Full text

Veterinary Medicine, Immunology, Immunopathology +16

Altered Gut Flora Are Associated with Septic Complications and Death in Critically Ill Patients with Systemic Inflammatory Response Syndrome

Kentaro Shimizu, Hiroshi Ogura, Toshimitsu Hamasaki et al. · Digestive Diseases and Sciences · 2010 · 211 citations · Full text

Veterinary Medicine, Immunology, Microbiology +10