Concepedia

New CCR5 variants associated with reduced HIV coreceptor function in southeast Asia

Corinne Métay, Liying Ma, Lien X Truong, Yasmine Dudoit, Pierre Versmisse, Ngai V Nguyen, Marie Nguyen, Daniel Scott‐Algara, Françoise Barré‐Sinoussi, Patrice Debré,

AIDS · 2004 · 29 citations · 36 references

DOI

Abstract

Among the five CCR5 variants found in this Vietnamese population, G106R and C269F displayed significant modifications of their receptor and coreceptor properties, which may contribute to susceptibility to HIV-1 infection and/or disease progression within this population.

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