Adenosine A1 and A2 receptor agonists reduce endotoxin-induced cellular energy depletion and oedema formation in the lung

Axel R. Heller, Juliane Rothermel, M. A. Weigand, Konstanze Plaschke, Joachim Schmeck, Martina Wendel, Hubert J. Bardenheuer, T. Koch

European Journal of Anaesthesiology · 2006 · 24 citations · 37 references

Abstract

Adenosine A1- and A2-receptor agonists reduced LPS-induced vasoconstriction and oedema formation by maintenance of tissue energy content. Thus, adenosine receptor stimulation, in particular of the A2 receptor, might be beneficial during acute lung injury.

References

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