Relationship between dose, blood level and haemodynamic response in patients with cirrhosis receiving propranolol

Propranolol for Prevention of Recurrent Gastrointestinal Bleeding in Patients with Cirrhosis

Didier Lebrec, Thierry Poynard, Patrick Hillon et al. · New England Journal of Medicine · 1981 · 518 citations

Medicine, Pharmacology, Pharmacotherapy +11

The Effect of Propranolol on Portal Hypertension in Patients With Cirrhosis: A Hemodynamic Study

Didier Lebrec, Patrick Hillon, Cristina Parrilla Muñoz et al. · Hepatology · 1982 · 275 citations

Medicine, Pharmacology, Pharmacotherapy +17

The Disposition of Propranolol

David G. Shand, Robert E. Rangno · Pharmacology · 2008 · 233 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Mechanism for reduced drug clearance in patients with cirrhosis

Dominique Pessayre, Didier Lebrec, Véronique Descatoire et al. · Gastroenterology · 1978 · 126 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +12

The Influence of Cirrhosis on Steady-State Blood Concentrations of Unbound Propranolol after Oral Administration1

Andrew J. Wood, David M. Kornhauser, G. Wilkinson et al. · Clinical Pharmacokinetics · 1978 · 82 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacology +13