Expansion of a Cell Population Expressing Stem Cell Markers in Parathyroid Glands From Patients With Hyperparathyroidism

Abstract

These novel findings demonstrate expansion of a resident cell population that expresses SC markers in abnormal parathyroid glands from patients with HPT. Our results suggest that clonal expansion of a resident SC population occurs in the pathogenesis not only of cancer, but also in benign parathyroid tumors occurring in HPT.