Tetrahedron Letters · 1989 · 42 citations · 16 references
Natural SciencesChemistryMedicinal ChemistryOrganic ChemistrySynthetic Medicinal ChemistryCarbonyl ChemistryHeterocyclic ChemistryNatural Product Drug DiscoveryOrganic SynthesisIsoquinoline AlkaloidsIsoquinoline ChemistryIsoquinoline SynthesisPlant AlkaloidsQuinoline Alkaloids
The central carbonyl of a vicinal tricarbonyl system is used as a dielectrophile with substituted phenethylamines in short, efficient syntheses of the isoquinoline alkaloids, papaveraldine, hydrastine and cordrastine.
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A simplified isoquinoline synthesis
Dale L. Boger, Christine E. Brotherton, Marshall D. Kelley · Tetrahedron · 1981 · 45 citations