Prostaglandin E2 promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor δ

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

Charles E. Eberhart, R J Coffey, Radhika Aramandla et al. · Gastroenterology · 1994 · 2.5K citations · Full text

Cyclooxygenase in biology and disease

Raymond N. DuBois, Steven B. Abramson, Leslie J. Crofford et al. · The FASEB Journal · 1998 · 2.5K citations

Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

Masanobu Oshima, Joseph Dinchuk, Stacia Kargman et al. · Cell · 1996 · 2.4K citations · Full text

Inflammation, Intestinal Polyposis, Medicine +9

Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

Masahiko Tsujii, Raymond N. DuBois · Cell · 1995 · 2.3K citations · Full text

Inflammation, Tumor Microenvironment, Cell Adhesion +13

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ

Barry M. Forman, Jasmine Chen, Ronald M. Evans · Proceedings of the National Academy of Sciences · 1997 · 2.1K citations

Metabolic Syndrome, Health Sciences, Biochemistry +14