Autoantibodies to polymorphonuclear neutrophil elastase do not inhibit but enhance elastase activity

Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro.

Ronald J. Falk, Regina S. Terrell, L Charles et al. · Proceedings of the National Academy of Sciences · 1990 · 1.3K citations

Life Sciences, Immunology, Pathology +17

Birmingham Vasculitis Activity Score (BVAS) in systemic necrotizing vasculitis.

Raashid Luqmani, P A Bacon, Robert J. Moots et al. · PubMed · 1994 · 1.1K citations

Medicine, Clinical Sciences, Internal Medicine +17

At the Crossroads of Chemistry and Immunology: Catalytic Antibodies

R.A. Lerner, Stephen J. Benkovic, Peter G. Schultz · Science · 1991 · 671 citations

Pharmacy, Chemistry, Immunology +17

Proof without prejudice: use of the Kolmogorov-Smirnov test for the analysis of histograms from flow systems and other sources.

Ian Young · Journal of Histochemistry & Cytochemistry · 1977 · 657 citations · Full text

Natural Sciences, Mathematics, Experimental Design +13

Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases.

Caroline A. Owen, M. A. Campbell, Philip L. Sannes et al. · The Journal of Cell Biology · 1995 · 384 citations · Full text

Life Sciences, Cell Biology, Immunology +16