Mitochondrial toxicity in HIV type-1-exposed pregnancies in the era of highly active antiretroviral therapy - Concepedia

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Publication | Open Access

Mitochondrial toxicity in HIV type-1-exposed pregnancies in the era of highly active antiretroviral therapy

DOI Full Paper Access

27

Citations

23

References

2008

Year

Andrea Gingelmaier, Thomas Grubert, Bernd Kost, Bernhard Setzer, Dirk Lebrecht, Ioannis Mylonas, Josef Mueller‐Hoecker, Udo Jeschke, S Hiedl, Klaus Friese,

Antiviral Therapy

Abstract

Placental tissue of HIV-1-infected ART-exposed pregnancies shows evidence of mtDNA depletion with secondary respiratory chain compromise. The clinical effects of this finding warrant further investigation.

References

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