Continuous but not intermittent olanzapine infusion induces vacuous chewing movements in rats

Positron Emission Tomographic Analysis of Central D1 and D2 Dopamine Receptor Occupancy in Patients Treated With Classical Neuroleptics and Clozapine

Lars Farde · Archives of General Psychiatry · 1992 · 1.4K citations

Relationship Between Dopamine D₂ Occupancy, Clinical Response, and Side Effects: A Double-Blind PET Study of First-Episode Schizophrenia

Shitij Kapur, Robert B. Zipursky, Corey Jones et al. · American Journal of Psychiatry · 2000 · 1.1K citations

Clinical and Theoretical Implications of 5-HT₂ and D₂ Receptor Occupancy of Clozapine, Risperidone, and Olanzapine in Schizophrenia

Shitij Kapur, Robert B. Zipursky, G Remington · American Journal of Psychiatry · 1999 · 710 citations

Antipsychotic Dosing in Preclinical Models Is Often Unrepresentative of the Clinical Condition: A Suggested Solution Based on in Vivo Occupancy

Shitij Kapur, Susan C. VanderSpek, Barbara A. Brownlee et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 474 citations

A Positron Emission Tomography Study of Quetiapine in Schizophrenia: A Preliminary Finding of an Antipsychotic Effect With Only Transiently High Dopamine D2 Receptor Occupancy

Shitij Kapur · Archives of General Psychiatry · 2000 · 398 citations