Concepedia

Basophil Interleukin 4 and Interleukin 13 Production Is Suppressed during the Early Phase of Rush Immunotherapy

Halina Plewako, Katarzyna Wosińska, Monica Arvidsson, Janne Björkander, Per Stahl Skov, Lena Håkansson, S. Rak

International Archives of Allergy and Immunology · 2006 · 68 citations · 26 references

DOI

Abstract

We report the decrease in blood basophil numbers, their lower activation status and the reduced production of IL-4 and IL-13 early in the course of RIT. This early suppression of basophil activation could be one mechanism behind the protective effect of RIT.

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Insect venom immunotherapy induces interleukin‐10 production and a Th2‐to‐Th1 shift, and changes surface marker expression in venom‐allergic subjects

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