Tolerance and outcome of patients with unresectable hepatocellular carcinoma treated with sorafenib

V. Ozenne, Valérie Paradis, Simon Pernot, Corinne Castelnau, Marie‐Pierre Vullierme, Mohamed Bouattour, Dominique Valla, Olivier Farges, Françoise Degos

European Journal of Gastroenterology & Hepatology · 2010 · 69 citations · 13 references

Abstract

Occurrence of adverse events is similar in Child-Pugh A and Child-Pugh B patients. Nevertheless, the survival of Child-Pugh B patients is very low. Whether liver function or tumor spread is responsible for mortality is unclear. Opportunity of treatment for Child-Pugh B patients is questionable. The immunophenotype of tumoral tissue was not predictive of survival.

References

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