Synthetic Communications · 2011 · 13 citations · 39 references
Bioorganic ChemistryFormal Asymmetric SynthesisEngineeringSynthetic StudiesNatural SciencesKey Intermediate 3Organic ChemistryL-malic AcidChemistryPharmacologySynthetic ChemistryEnantioselective SynthesisBiomolecular EngineeringNatural Product Synthesis
A formal asymmetric synthesis of (+)-3-demethoxyerythratidinone (1) is reported using the key intermediate 3 as the starting material, which is available from L-malic acid by a known method. Keywords: Erythrina alkaloidformal total synthesis N-acyliminium cyclization ACKNOWLEDGMENT This work was supported by a grant from the Kyung Hee University in 2007 (KHU-20070663).
39