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Cytomegalovirus-induced salivary gland pathology: resistance to kinase inhibitors of the upregulated host cell EGFR/ERK pathway is associated with CMV-dependent stromal overexpression of IL-6 and fibronectin

Michael Melnick, Parish P. Sedghizadeh, Krysta A. Deluca, Tina Jaskoll

Herpesviridae · 2013 · 10 citations · 24 references

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Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors

Timothy R. Wilson, Jane Fridlyand, Yibing Yan et al. · Nature · 2012 · 1.1K citations · Full text

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Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins

Orit Rozenblatt–Rosen, Rahul C. Deo, Megha Padi et al. · Nature · 2012 · 394 citations · Full text

The Mammalian MAPK/ERK Pathway Exhibits Properties of a Negative Feedback Amplifier

Oliver Sturm, Richard Orton, Joan Grindlay et al. · Science Signaling · 2010 · 250 citations · Full text

Amplification of the Driving Oncogene, <i>KRAS</i> or <i>BRAF</i> , Underpins Acquired Resistance to MEK1/2 Inhibitors in Colorectal Cancer Cells

Annette S. Little, Kathryn Balmanno, Matthew J. Sale et al. · Science Signaling · 2011 · 204 citations

<i>CRTC1/MAML2</i> fusion transcript in high grade mucoepidermoid carcinomas of salivary and thyroid glands and Warthin's tumors: Implications for histogenesis and biologic behavior

Yamilet Tirado, Michelle D. Williams, Ehab Y. Hanna et al. · Genes Chromosomes and Cancer · 2007 · 198 citations