Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

Inducible Gene Targeting in Mice

Ralf Kühn, Frieder Schwenk, Michel Aguet et al. · Science · 1995 · 1.9K citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis

Tsukasa Okuda, Jan M. van Deursen, Scott W. Hiebert et al. · Cell · 1996 · 1.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.

Qing Wang, Terryl Stacy, Michael Binder et al. · Proceedings of the National Academy of Sciences · 1996 · 1.2K citations

Life Sciences, Genetics, Molecular Genetics +14

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

Woo‐Joo Song, Melanie G. Sullivan, Robert D. Legare et al. · Nature Genetics · 1999 · 1.1K citations

Life Sciences, Genetics, Molecular Genetics +8

Granulocytic sarcoma: A clinicopathologic study of 61 biopsied cases

Richard S. Neiman, Maurice Barcos, Costan W. Berard et al. · Cancer · 1981 · 971 citations · Full text

Medicine, Oncology, Pathology +14