Concepedia

Magnesium Sulfate Prevents Remifentanil-Induced Postoperative Hyperalgesia in Patients Undergoing Thyroidectomy

Jong Wook Song, Youn-Woo Lee, Kyung Bong Yoon, Soo Jung Park, Yon Hee Shim

Anesthesia & Analgesia · 2011 · 103 citations · 32 references

DOIFull text

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Abstract

A relatively high dose of intraoperative remifentanil enhances periincisional hyperalgesia. Intraoperative MgSO(4) prevents remifentanil-induced hyperalgesia. However, hyperalgesia did not reach clinical relevance in terms of postoperative pain or analgesic consumption in patients undergoing thyroidectomy.

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