BMS-777607 promotes megakaryocytic differentiation and induces polyploidization in the CHRF-288-11 cells

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

CB Lozzio, BB Lozzio · Blood · 1975 · 2.8K citations

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

CB Lozzio, BB Lozzio · Blood · 1975 · 2.3K citations · Full text

The biological significance of platelet volume: Its relationship to bleeding time, platelet thromboxane B2 production and megakaryocyte nuclear DNA concentration

John F. Martin, E. A. Trowbridge, Geraldine L. Salmon et al. · Thrombosis Research · 1983 · 467 citations

Platelet Biology, Thrombosis, Thrombopoiesis +10

Platelets generated in vitro from proplatelet-displaying human megakaryocytes are functional

ES Choi, JL Nichol, MM Hokom et al. · Blood · 1995 · 369 citations · Full text

Discovery of <i>N</i>-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase Superfamily

Gretchen M. Schroeder, Yongmi An, Zhen‐Wei Cai et al. · Journal of Medicinal Chemistry · 2009 · 276 citations · Full text

Orally Efficacious Inhibitor, Drug Target, Pharmacotherapy +21