Ternary complexes of cis-(NH3)2Pt(II) with model nucleobases (1-methylcytosine, 9-methylguanine) and N- and O-bound amino acids (gly, ala)

DNA-protein and DNA interstrand cross-linking by cis- and trans-platinum(II) diamminedichloride in L1210 mouse leukemia cells and relation to cytotoxicity.

Leonard A. Zwelling, Tom Anderson, Kurt W. Kohn · PubMed · 1979 · 396 citations

Pharmacy, Cancer Biology, Molecular Biology +16

The mechanism of action of platinum antitumor drugs

J. Reedijk · Pure and Applied Chemistry · 1987 · 276 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Inhibition of cis-platinum nephrotoxicity by diethyldithiocarbamate rescue in a rat model.

Richard F. Borch, M E Pleasants · Proceedings of the National Academy of Sciences · 1979 · 237 citations · Full text

Pharmacy, Toxicology, Renal Pathophysiology +13

Structure-stability relationship in ternary copper(II) complexes involving aromatic amines and tyrosine or related amino acids. Intramolecular aromatic ring stacking and its regulation through tyrosine phosphorylation

Osamu Yamauchi, Akira Odani · Journal of the American Chemical Society · 1985 · 157 citations

Natural Sciences, Chemistry, Inorganic Chemistry +12

Chemistry and molecular biology of platinum anticancer drugs

Stephen J. Lippard · Pure and Applied Chemistry · 1987 · 147 citations · Full text

Medicine, Cancer Biology, Medicinal Chemistry +14