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Modulation of 11β-Hydroxysteroid Dehydrogenase (11βHSD) Activity Biomarkers and Pharmacokinetics of PF-00915275, a Selective 11βHSD1 Inhibitor

DOIFull Paper Access

90

Citations

15

References

2007

Year

Rachel Courtney, Paul M. Stewart, Melvin Toh, Marie-Noella Ndongo, Roberto A. Calle, Boaz Hirshberg
The Journal of Clinical Endocrinology & Metabolism

Abstract

PF-00915275 was safe at all doses tested. The results of the prednisolone generation test and the urinary metabolite ratios confirm that PF-00915275 is a selective 11betaHSD1 inhibitor.

References

YearCitations

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