Construction of a 2.5-Mb Integrated Physical and Gene Map of Distal 21q22.3

A comprehensive genetic map of the human genome based on 5,264 microsatellites

Colette Dib, Sabine Fauré, Cécile Fizames et al. · Nature · 1996 · 3K citations

Genetic Analysis, Haplotype Determination, Medicine +10

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector.

H. Shizuya, Bruce W. Birren, U J Kim et al. · Proceedings of the National Academy of Sciences · 1992 · 1.7K citations · Full text

Genetics, Bacteriology, Bacteriophage +22

A new bacteriophage P1–derived vector for the propagation of large human DNA fragments

P.A. loannou, Chris T. Amemiya, Jeffrey Garnes et al. · Nature Genetics · 1994 · 849 citations

Natural Sciences, Bacteriophage, Dna Replication +4

Down syndrome phenotypes: the consequences of chromosomal imbalance.

Julie R. Korenberg, X N Chen, Roberton D. Schipper et al. · Proceedings of the National Academy of Sciences · 1994 · 788 citations · Full text

Down Syndrome, Chromatin, Developmental Biology +13

Identification of deletion mutations and three new genes at the familial polyposis locus

Geoff Joslyn, M. Carlson, Andrew Thliveris et al. · Cell · 1991 · 767 citations

New Genes, Familial Polyposis Locus, Genetic Disorder +8