Streptokinase vs alteplase in massive pulmonary embolism: A randomized trial assessing right heart haemodynamics and pulmonary vascular obstruction

Abstract

These results proved that, when the full dose of streptokinase has been given over 12 h, its efficacy is as good as that of 2 h of recombinant tissue plasminogen. A further trial aimed at comparing recombinant tissue plasminogen activator and streptokinase infused over a 2 h period is needed to determine whether a similar efficacy can be obtained.