Applied Physics Letters · 2011 · 195 citations · 10 references
Natural SciencesBiomedical EngineeringRadiologyBiomedical ImagingMagnetic MaterialsNanomaterialsMagnetic CharacterizationMagnetic NanomaterialsMagnetic Resonance ImagingMagnetic Resonance Imaging PhysicsMagnetization ProcessesNanomedicineMagnetic ImagingMagnetic NanoparticlesMagnetic Particle ImagingMagnetic PropertiesNanoparticle Imaging AgentsNanoparticle-based Contrast AgentsNanoparticlesParticle-size Distribution
Spatial and temporal resolution of magnetic particle imaging (MPI), a powerful technique for biomedical imaging, depends crucially on the magnetic properties of the magnetic nanoparticle (MNP) tracer. The authors establish the relation of the static and the dynamic magnetization behavior of various MNP preparations to their MPI performance. While MNPs with a mean diameter of 6 nm achieve only 0.2% of the theoretical maximum amplitude of the third harmonic (at 25 kA/m drive field strength), those with 19 nm diameter attain 57%. The good performance of Resovist, a clinically approved contrast agent for magnetic resonance imaging, is explained by the presence of MNP aggregates.
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In vivo cancer targeting and imaging with semiconductor quantum dots
Xiaohu Gao, Yuanyuan Cui, Richard M. Levenson et al. · Nature Biotechnology · 2004 · 4.7K citations