JAMA · 1961 · 21 citations · 3 references
MedicineCardiologyEndocrinologyEndocrine Nuclear MedicineRadionuclide TherapyTherapeutic Nuclear MedicineRadioiodine TherapyRadionuclide Therapy PrinciplesRadiopharmaceutical TherapyThyroid ImagingThyroid ScintigraphyThyroid Uptake StudiesDiffuse Nontoxic GoiterIodine-123 ImagingIodine-131 ScintigraphyPatient Choice Of TreatmentRadioactive Iodine Therapy CareRadionuclide Thyroid ImagingRecurrenceThyroid Radionuclide Uptake
Hyperthyroidism was treated with I131 in 1,603 cases. These included cases of diffuse toxic goiter and nodular goiter with hyperthyroidism. There were 187 patients with congestive heart failure, 30 with angina pectoris, and 32 with combined angina pectoris and congestive failure. In addition, there were 107 patients with atrial fibrillation but without congestive failure or angina. Radioiodine was the only treatment used for the hyperthyroid state. The cardiac status was strikingly improved in all groups studied. The number of treatments and incidence of myxedema was almost the same for the cardiac and noncardiac patients. The total administered dose averaged 7.0 millicuries for the entire series and 11.5 for the cardiac patients. The recurrence rate was less than 1%. The authors believe that I<sup>131</sup>is the treatment choice for thyrocardiac disease.
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